TRIVALENT ION CROSS-LINKED AND ACETALATED GELLAN GUM MICROSPHERES OF GLIMEPIRIDE
نویسندگان
چکیده
منابع مشابه
Enhanced gelation properties of purified gellan gum.
Gellan gum is a hydrogel-forming polysaccharide when combined with monovalent or divalent cations such as sodium, magnesium, potassium or calcium. Commercially, gellan gums are sold with trace amounts of these cations, which have been proven to affect the gelation and mechanical properties of the resultant hydrogels. A new method based on impedance analysis for determining the gel transition te...
متن کاملElectrically conducting PEDOT:PSS - gellan gum hydrogels
Hydrogels consisting of the conducting polymer PEDOT:PSS and the biopolymer gellan gum (GG) were characterized using electrical, mechanical and rheological methods. Compression testing and rheological analysis showed that the gels weakened with increasing PEDOT:PSS content. In contrast, the increasing PEDOT:PSS content resulted in an increasing electrical conductivity. Disciplines Medicine and ...
متن کاملPreparation and Evaluation of Soft Gellan Gum Gel Containing Paracetamol
The objective of this study was to develop soft paracetamol gel using gellan gum as a gelling agent and sodium citrate as a source of cation. Different batches were prepared using three different concentrations of gellan gum (0.1, 0.3, and 0.5%), each with two different sodium citrate concentrations (0.3 and 0.5%). The consistency of the paracetamol gel was dependent on the concentration of gel...
متن کاملThe Mucosal Adjuvant Potential of Cross-Linked Dextran Microspheres as Dry Powder
Objective(s) The immunoadjuvant potential of cross-linked dextran microspheres (CDM) as absorption enhancer and Quillaja saponins (QS) as immunomodulator adjuvant was evaluated. Materials and Methods CDM loaded or tetanus-mixed toxoid (TT) or Quillaja saponin (QS) were nasally administered to rabbits in dry powder form, three times in 2 weeks interval and serum IgG and nasal lavage sIgA tite...
متن کاملModified Gellan Gum hydrogels with tunable physical and mechanical properties.
Gellan Gum (GG) has been recently proposed for tissue engineering applications. GG hydrogels are produced by physical crosslinking methods induced by temperature variation or by the presence of divalent cations. However, physical crosslinking methods may yield hydrogels that become weaker in physiological conditions due to the exchange of divalent cations by monovalent ones. Hence, this work pr...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Asian Journal of Pharmaceutical and Clinical Research
سال: 2020
ISSN: 2455-3891,0974-2441
DOI: 10.22159/ajpcr.2020.v13i5.37229